EVALUATING A NOVEL BIOACTIVE GLASS TOOTHPASTE FOR MANAGING DENTIN HYPERSENSITIVITY IN PATIENTS UNDERGOING ORTHODONTIC TREATMENT
Keywords:
Bioactive Glass, Dentin Hypersensitivity; , Desensitizing Agents, Orthodontics, Pain Measurement, Randomized Controlled Trial, ToothpastesAbstract
Background: Dentin hypersensitivity is a common clinical concern among orthodontic patients, often exacerbated by tooth movement and enamel surface changes. Conventional desensitizing toothpastes offer varying degrees of relief, yet many patients continue to experience discomfort. Bioactive glass–based formulations have emerged as promising alternatives due to their ability to occlude dentinal tubules and promote mineral deposition, potentially offering enhanced symptom reduction.
Objective: To evaluate the efficacy of a novel bioactive glass toothpaste in reducing dentin hypersensitivity among orthodontic patients compared with a standard desensitizing toothpaste.
Methods: A randomized controlled trial was conducted involving participants undergoing fixed orthodontic treatment who reported dentin hypersensitivity. Individuals were randomly allocated to either the intervention group using a bioactive glass toothpaste or the control group using a standard desensitizing toothpaste. Pain intensity was assessed at baseline, week 2, and week 4 using a standardized Visual Analog Scale (VAS) following thermal and tactile stimuli. Demographic data and all outcome measures were analyzed using appropriate comparative statistical tests.
Results: Participants in the bioactive glass group showed greater reductions in mean VAS scores compared with the control group at both follow-up points. By week 4, the intervention group demonstrated a substantial decline in hypersensitivity levels, whereas the control group exhibited only moderate improvement. Across both assessment modalities, statistically significant between-group differences were observed, indicating superior performance of the bioactive glass formulation.
Conclusion: The novel bioactive glass toothpaste produced a more pronounced reduction in dentin hypersensitivity than the standard desensitizing toothpaste in orthodontic patients. These findings support its potential as an effective adjunct for managing sensitivity during orthodontic treatment.
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Copyright (c) 2025 Fatima Tu Zohra, Aiman Zahra , Abdul Wahab Ali (Author)
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